Which joint care supplement is the best? I have seen a wide array available at stores, each boasting that they are the best. While I can’t say how most of them work, I can say that Celadrin has been tested and proven to work in several clinical studies. Celadrin is a joint pain supplement that is unique in composition and offers relief up to six-times faster than its competitors. Not only is it available in an oral supplement, but there is also a cream that works through the skin to ease away pain. It’s FDA approved and has yet to cause any side effects, and there are more than half a billion sold! When it comes to my joint pain, I trust Celadrin to ease my swollen and inflamed joints!